The recent revelation of former President Joe Biden’s diagnosis of advanced, aggressive prostate cancer that has metastasized to the bones has caused deep sorrow and concern. A physician with decades of experience treating and researching prostate cancer expressed heartbreak over the news, particularly because the disease could potentially have been detected earlier through timely screening. “His condition could have potentially been diagnosed at an earlier stage, when a cure is possible,” the physician remarked.
Prostate cancer continues to be the most common cancer among men and the second leading cause of cancer-related deaths. The typical age for diagnosis is 67, yet despite this, a startling number of primary care physicians in the U.S.—more than half—do not routinely offer the PSA (prostate-specific antigen) blood test or digital rectal exam (DRE). These are two straightforward tools that, when used appropriately and consistently, have saved countless lives.
The reason behind this lapse can be traced back to recommendations from the United States Preventive Services Task Force (USPSTF). In 2012, and again in 2018, the USPSTF advised against prostate cancer screening for men over 70 years of age. The recommendations, issued by a panel notably lacking urologists, were based on studies that have since been criticized as flawed and statistically unsound. A particularly concerning issue is that these studies had very low participation rates among Black men, a group significantly more susceptible to aggressive prostate cancer and higher mortality rates from the disease.
Before the issuance of these recommendations, prostate cancer screening had been standard for over two decades and had led to a nearly 50% reduction in death rates from the disease. Since 2013, however, mortality has been climbing. According to the American Cancer Society, prostate cancer deaths have risen year after year. In 2024 alone, 35,250 men in the United States died from the disease. Of those, a striking 60% were men aged 70 and older—the very group that was excluded from screening under the USPSTF guidelines.
This tragic outcome highlights a worsening trend: prostate cancer is increasingly being caught at advanced, often incurable, stages. Older men, Black men, and those with a family history of prostate cancer are particularly at risk. Globally, the numbers are equally sobering. In 2022, there were 1.5 million new cases and over 306,000 deaths due to prostate cancer.
When prostate cancer spreads to other parts of the body—most commonly the bones—it becomes incurable. The prognosis in such cases is grim: 79% of men with metastatic prostate cancer ultimately die from it, and 60% of those die within just two years of diagnosis. These are preventable deaths. Proper screening and timely detection can make a dramatic difference in outcomes.
Critics of widespread screening often point to the risk of overdiagnosis and unnecessary treatment. While this concern was more relevant in the past, modern medical advancements have significantly improved the ability to distinguish between aggressive and slow-growing tumors. Tools such as MRI of the prostate, PSMA PET/CT imaging, genomic testing, and improved biopsy techniques have refined diagnostic precision. Additionally, active surveillance—where low-risk cases are monitored instead of treated immediately—is now a well-established practice, helping many men avoid unnecessary interventions.
Still, the limitations of current diagnostic methods must be acknowledged. “Prostate biopsies can underestimate the severity of the cancer in about 50% of cases,” the physician stated. Even with active surveillance, nearly half of men eventually see their cancer progress to a more serious stage that requires treatment. This reality makes it clear that avoiding screening in older men—many of whom are still active and healthy with a life expectancy of more than 14 years—is not only unjustified but dangerous.
From an economic standpoint, the costs are staggering. In 2010, the Centers for Medicare & Medicaid Services (CMS) spent $11.8 billion on prostate cancer care. By 2020, that figure had soared to $20 billion. Treating metastatic prostate cancer alone can cost more than $200,000 per patient. In contrast, early detection and treatment are far more cost-effective. The five-year survival rate for localized prostate cancer is over 99%. For men diagnosed with metastatic disease, that number falls dramatically to 37%.
In May 2024, a paper co-authored by the physician and Dr. Vladimir Ioffe, published in Trends in Urology, referenced over 50 studies and advocated for routine screening in healthy men over 70. This position is gaining support among urologists and oncologists who see the damage done by late-stage diagnoses. “Thankfully, CMS does cover prostate cancer screening costs for Medicare beneficiaries,” the physician noted. However, current guidelines still dissuade many doctors from offering these screenings to patients over 70, even when clinical evidence supports it.
Today, more than 3.3 million men in the U.S. are alive after being treated for prostate cancer. This figure underscores the effectiveness of early detection. Meanwhile, the U.S. is home to approximately 24 million men over the age of 70. Many in this group are capable of living well into their 80s and beyond. By not screening them, the healthcare system is denying them a potentially life-saving intervention.
“It is time to update our national guidelines to reflect medical reality,” the physician urged. In their view, all men over the age of 55 should receive regular prostate cancer screening, particularly those with risk factors such as a family history of the disease or African ancestry.
The case of President Biden, though deeply personal and tragic, sheds light on a national health policy failing that has put countless men at risk. With the tools of modern medicine readily available and the clinical evidence increasingly in favor of routine screening, it is time for the guidelines to change. Without such updates, preventable deaths will continue, and opportunities for early, life-saving intervention will be missed.
The medical community and policy makers must come together to reverse this dangerous course. Screening saves lives. The data is clear. The time to act is now.

(Dr. Navin C. Shah is a urologist based in the Washington, D.C., area. He has published six papers on prostate cancer and 15 letters to the editor commenting on other published papers on prostate cancer in various reputed US urology journals. His memoir, “Karma and Destiny of an Indian American Surgeon” (published by AB Books), was released in 2022. Dr. Shah is also a numismatist with a collection of thousands of ancient Indian coins.)