President-elect Donald Trump has announced Dr. Jay Bhattacharya, a Stanford University health researcher, as his choice for the next director of the National Institutes of Health (NIH). Dr. Bhattacharya, a physician and health economist, will require Senate confirmation to assume the role. The NIH, which employs over 18,000 people and allocates nearly $48 billion annually in scientific research funding, could see significant changes under his leadership.
“Together, Jay and RFK Jr. will restore the NIH to the Gold Standard of Medical Research as they examine the underlying causes of, and solutions to, America’s biggest Health challenges, including our Crisis of Chronic Illness and Disease. Together, they will work hard to Make American Healthy Again!” Trump stated while announcing the nomination.
If confirmed, Bhattacharya will lead the world’s largest public funder of biomedical research at a time when the NIH may face restructuring as part of broader government reforms. Historically supported by both political parties, the NIH faced proposed budget cuts under Trump’s first administration. During the COVID-19 pandemic, the agency drew sharp criticism from some Republicans, a sentiment that persists toward its former leaders, Dr. Anthony Fauci and Dr. Francis Collins.
Bhattacharya gained attention during the pandemic for co-authoring “The Great Barrington Declaration,” a controversial open letter released in October 2020. The document criticized lockdowns and mask mandates, advocating for herd immunity by allowing low-risk populations to become infected while protecting the vulnerable. Public health experts widely condemned it, with Collins describing it as “dangerous” and “fringe.” Dr. Gregory Poland, president of the Atria Academy of Science & Medicine, expressed concern about Bhattacharya’s appointment, stating, “They were wrong. So it is concerning.”
Virologist Angela Rasmussen of the University of Saskatchewan offered a harsher critique, stating, “I don’t think that Jay Bhattacharya belongs anywhere near the NIH, much less in the director’s office. That would be absolutely disastrous for the health and well-being of the American public and actually the world.”
However, Bhattacharya’s supporters argue his leadership could bring necessary reforms to the NIH. Kevin Bardosh, head of Collateral Global, praised him as a “visionary leader” who could challenge the NIH’s perceived “culture of groupthink.” Similarly, Martin Kulldorf, one of Bhattacharya’s co-authors of the declaration, commended him as an evidence-based scientist capable of restoring the NIH’s integrity.
Dr. Ashish Jha, who served as President Biden’s COVID-19 Response Coordinator, offered a more balanced perspective. “There were times during the pandemic where he took a set of views that were contrary to most people in the public health world, including my own views. But he’s fundamentally a very smart, well-qualified person,” Jha noted. He added that while Bhattacharya holds controversial views, his overall body of work places him within the scientific mainstream.
Bhattacharya’s potential tenure coincides with other controversial appointments, including Robert F. Kennedy Jr., a known critic of vaccines and mainstream medicine, as the likely head of the Department of Health and Human Services. Kennedy has suggested replacing hundreds of NIH employees. Jha highlighted the challenge Bhattacharya may face working under Kennedy, noting, “He’ll have to deal with a boss who holds deeply unscientific views. That will be a challenge for Jay Bhattacharya but I suspect that will be a challenge for anybody who becomes the head of NIH.”
Proposals to restructure the NIH are already being discussed by Republican lawmakers and conservative think tanks. One idea involves consolidating the NIH’s 27 institutes and centers into 15, while another suggests implementing term limits for NIH leaders. Critics argue these changes could undermine the agency’s mission. Kulldorf, however, believes reforms are essential, stating, “In the United States, we abandoned evidence-based medicine during the pandemic. Therefore, there’s now enormous distrust… NIH has an important role to restore the integrity in medical research and public health research.”
Other proposed reforms include giving states block grants to allocate research funding, bypassing the NIH’s peer-review system. While some view this as a way to decentralize decision-making, others fear it could reduce the NIH’s budget and compromise the quality of research. Rasmussen voiced concerns, saying, “What I worry about is that if somebody like Jay Bhattacharya comes in to ‘shake up’ the NIH, they’re going to dismantle the NIH and prevent it from actually doing its job rather than just carry out constructive reforms.”
The Trump administration’s potential approach to certain types of research could further complicate matters. Fields like “gain-of-function” research, which examines how pathogens become more dangerous, may face stricter oversight. Some experts, like Daniel Correa of the Federation of American Scientists, support tighter lab security and oversight, stating, “Tightening lab security and revisiting and strengthening oversight over risky research… would be welcome.”
However, concerns exist that other areas of research, such as studies involving fetal tissue, could face renewed restrictions. Dr. Lawrence Goldstein of the University of California, San Diego, warned against such bans, explaining, “If Americans want to see rapid research on repairing organ damage and brain damage and all the other diseases we’re trying to fight, fetal tissue is a really important part of that toolbox.”
Bhattacharya’s nomination comes at a time of heightened political scrutiny of the NIH. The agency’s role in the pandemic response, including controversial guidance on masks and vaccines, made it a lightning rod for criticism. Fauci, in particular, became both a celebrated figure and a target for attacks, especially regarding his stance on the virus’s origins.
As Bhattacharya awaits Senate confirmation, debates over the NIH’s future continue. His critics worry about the agency’s direction under his leadership, while his supporters see an opportunity for meaningful change. Whether his appointment will bring constructive reforms or contentious disruptions remains to be seen.