American hospitals have earned a prominent place among the world’s top medical institutions, according to the recently published World’s Best Hospitals 2025 ranking by Newsweek in collaboration with Statista, a global data research firm.
This comprehensive list spans more than 2,400 hospitals from 30 different nations. While each country’s ranking is tailored to local data and methodology, Newsweek’s overall Global Top 250 brings together the best hospitals from across all participating countries, creating a definitive list of the world’s top medical centers.
In this elite group, the Mayo Clinic in Minnesota claimed the number one position globally, with the Cleveland Clinic in Ohio following as the second-best. Also featured prominently in the Global Top 10 were the Johns Hopkins Hospital in Maryland and Massachusetts General Hospital in Massachusetts, underscoring the dominance of U.S. healthcare facilities.
Hospitals in this ranking were evaluated using a multi-faceted scoring system that incorporated insights from over 85,000 healthcare professionals through peer surveys. These assessments were combined with patient experience information, institutional performance indicators, and findings from Statista’s Patient-Reported Outcome Measures (PROM) survey. This PROM component evaluates how hospitals use patient feedback to improve their quality of care. Criteria ranged from patient ratings and staff courtesy to accreditation and even the standard of cafeteria food.
Lukas Kwietniewski of Statista emphasized the evolving priorities in modern healthcare when speaking to Newsweek’s Health Care Editor Alexis Kayser in a February interview. “We have a long-term plan that we want to follow the trends that are going on in healthcare, not only nationally, but also internationally,” Kwietniewski said. “There is a shift towards patient-centered care. It has been ongoing now for at least a decade and that is also what leading hospitals are more and more aspiring to deliver – to have that patient centricity.”
The United States stands out in this global evaluation with a staggering 430 hospitals making the rankings—the highest of any country featured. The Top 10 U.S. hospitals, which include several recurring names known for their cutting-edge research and exceptional patient care, are as follows:
Mayo Clinic in Rochester, Minnesota
Cleveland Clinic in Cleveland, Ohio
The Johns Hopkins Hospital in Baltimore, Maryland
Massachusetts General Hospital in Boston, Massachusetts
Ronald Reagan UCLA Medical Center in Los Angeles, California
Stanford Health Care – Stanford Hospital in Stanford, California
The Mount Sinai Hospital in New York, New York
Brigham and Women’s Hospital in Boston, Massachusetts
Cedars-Sinai Medical Center in Los Angeles, California
Northwestern Memorial Hospital in Chicago, Illinois
An accompanying infographic highlights how hospitals are distributed by state, with California leading the nation. The Golden State boasts 41 hospitals on the U.S. list—more than any other state. Texas follows with 29 hospitals, trailed by Pennsylvania at 26, Illinois with 21, and both Ohio and Florida with 20 each.
Unsurprisingly, many of the highest-ranked hospitals in these states are either part of expansive healthcare systems or affiliated with prestigious universities. For example, Ronald Reagan UCLA Medical Center is California’s top-rated institution, while Northwestern Memorial Hospital ranks highest in Illinois. In Pennsylvania, the Hospital of the University of Pennsylvania holds the top spot.
Cleveland Clinic, recognized as the world’s second-best hospital, leads Ohio’s healthcare landscape. Florida’s highest-ranked facility is the Mayo Clinic in Jacksonville, a regional branch of the globally top-ranked institution in Minnesota.
Interestingly, three U.S. states—Nevada, Mississippi, and Vermont—were not assessed and therefore have no hospitals represented in this year’s global ranking.
Each country’s list in the World’s Best Hospitals 2025 ranking was generated based on the best data available within that nation. The elements considered include patient satisfaction, quality of care indicators, and staffing statistics, though the depth and type of available data vary greatly from one country to another. As a result, the methodologies for ranking hospitals differ by country, with the overall goal of making each list as accurate and locally relevant as possible.
In the United States, data was drawn from multiple public sources to ensure a reliable assessment. According to the American Hospital Association, there are currently 6,120 hospitals in the U.S., most of which are categorized as non-federal, short-term general hospitals. These encompass nonprofit organizations, private companies, and institutions managed by state or local governments.
To develop the U.S. ranking, Statista relied heavily on metrics from the Medicare “Hospital Compare” dataset, a tool published by the Centers for Medicare & Medicaid Services (CMS). CMS evaluates hospital performance using a range of indicators including mortality rates, safety of care, readmission rates, patient experience, and the timeliness and effectiveness of treatments.
Patient satisfaction was gauged through responses collected in October 2024 as part of Medicare’s Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. Notably, this year marked the first time the CMS data on Health Equity and Patient Reported Outcomes were incorporated into the World’s Best Hospitals ranking, further enriching the evaluation framework.
American hospitals have once again demonstrated their leadership in global healthcare through a combination of cutting-edge research, patient-centered approaches, and rigorous standards. With institutions like the Mayo Clinic and Cleveland Clinic not only topping U.S. lists but also standing tall on the international stage, the 2025 rankings affirm the strength and excellence of the American healthcare system.